You can fly into the Kirksville Airport, just 5 miles north of the hotel. Free shuttle service is provided from the Kirsville airport to the hotel. Click here for schedules and information on shuttle flights from St. Louis, Missouri. For on-line reservations into Kirksville, visit: www.capeair.com or call (660) 627-0100 or 866-Cape-Air (866-227-9247). You may book your Cape Air tickets to/from Kirksville as a codeshare through American Airlines and earn AAdvantage miles for your trip. Simply go to www.aa.com to book from your home airport all the way through to Kirksville. In the flight search box, be sure to click "More Search Options" then select "All Carriers" from the "Select Carrier" drop-down menu. You may also book your Cape Air tickets in conjunction with many other airlines, along with your Depot Inn and Suites hotel reservation, by calling our Complete Travel Arrangements line at 877-459-5900 or 660-616-4870, or by booking through www.expedia.com.

If you are a private pilot, you can also fly directly into Kirksville. Car rental service is also available at the Kirksville Aiport. Click here to make an online reservation with Enterprise Car Rentals. For one stop Amtrak, car rental, and hotel reservations, call the "Complete Travel Arrangements" toll-free phone number listed below.

Alternatively, you can fly into Kansas City (MCI), St. Louis (STL) or Des Moines (DSM), rent a car, and drive to La Plata. Many major airlines serve all three of these international airports from around the nation and around the globe. Most major car rental agencies are located at all three airports and most are open around the clock. Click the links below for driving directions from any of the three airports. For one stop flight, car rental, and hotel reservations, call the "Complete Travel Arrangements" toll-free phone number listed below.

Click here for map & driving directions from the Kansas City International Airport (MCI)
176 miles – about 3 hours 10 minutes.

Click here for map & driving directions from the St. Louis International Airport (STL)
186 miles – about 3 hours 8 minutes.

Click here for map & driving directions from the Des Moines International Airport (DSM)
164 miles - about 3 hours 33 minutes.

Start address: Kansas City Airport
End address: Depot Inn & Suites 1245 N Brown St La Plata, MO 63549

Start at: Kansas City Airport

1. Head west on Paris St toward London Dr - 0.1 mi
2. Turn right to merge onto NW Cookingham Dr/NW LP Cookingham Dr - 1.4 mi
3. Merge onto I-29 S/US-71 S via the ramp to Kansas City - 12.7 mi
4. Take exit 1B to merge onto I-35 N - 46.3 mi
5. Take exit 54 for US-36 toward Cameron/Hamilton - 0.3 mi
6. Turn right at US-36 (signs for Hamilton) - 37.7 mi
7. Continue on MO-36 - 6.1 mi
8. Continue on US-36 - 3.2 mi
9. Continue on MO-36 - 7.2 mi
10. Continue on MO-139/US-36 Continue to follow US-36 - 4.8 mi
11. Continue on MO-36/MO-5 Continue to follow MO-5 - 10.4 mi
12. Continue on MO-129/US-36 Continue to follow US-36 - 25.8 mi
13. Take the US-63 ramp to Macon/Kirksville - 0.1 mi
14. Turn left at US-63 (signs for Kirksville) Continue to follow US-63 - 20.1 mi
15. Turn left onto St Hwy D (N Brown St)

Start address: Lambert - St Louis Airport
End address: Depot Inn & Suites 1245 N Brown St La Plata, MO 63549

Start at: Lambert - St Louis Airport

1. Head NW on Departing Flights/Terminal Access Rd toward Lambert Intl Blvd - 0.2 mi
2. Turn left at Lambert International Blvd - 351 ft
3. Take the ramp to I-70 W - 443 ft
4. Keep right at the fork, follow signs for I-70 W and merge onto I-70 W - 107 mi
5. Take exit 128A for US-63 S toward Moberly/Jefferson City - 0.1 mi
6. Keep right at the fork to continue toward Old 63 and merge onto Old 63 - 0.4 mi
7. Take the ramp onto US-63 N - 6.5 mi
8. Continue on MO-63 - 7.7 mi
9. Continue on MO-124/US-63 Continue to follow MO-124 - 9.0 mi
10. Continue on US-63 - 54.9 mi
11. Turn left at St Hwy D (N Brown St)

Start address: Des Moines International Airport
End address: Depot Inn & Suites 1245 N Brown St La Plata, MO 63549

Start at: Des Moines International Airport

1. Head south on SW 42nd St toward SW 64th Ave/Army Post Rd - 0.5 mi
2. SW 42nd St turns slightly right and becomes SW 64th Ave/Army Post Rd - 1.2 mi
3. Turn left at IA-28 - 1.1 mi
4. Take the ramp onto IA-5 S - 6.5 mi
5. Continue on US-65 N - 2.1 mi
6. Take the State Hwy 5 exit toward Carlisle - 0.8 mi
7. Merge onto IA-5 - 18.3 mi
8. Turn left at IA-5/IA-92 Continue to follow IA-92 - 10.6 mi
9. Take exit 60 for IA-5 S toward Albia/Knoxville - 0.5 mi
10. Turn right at IA-5 (signs for Albia) - 25.9 mi
11. Turn left at IA-34 - 21.2 mi
12. Continue on US-34/US-63 - 0.6 mi
13. Slight left at US-34 - 0.1 mi
14. At the traffic circle, take the 1st exit onto US-63 - 1.0 mi
15. Continue on IA-63 - 15.5 mi
16. Continue on US-63/Weaver Rd Continue to follow US-63 - 2.1 mi
17. Turn right at IA-2/IA-63 - 4.8 mi
18. Turn left at US-63 Entering Missouri - 51.4 mi
19. Turn right at St Hwy D (N Brown Street) - 141 ft